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Introduction

The Centre for Longitudinal Studies (CLS) maintains genetic data from four British birth cohorts: the 1958 National Child Development Study (NCDS), the 1970 British Cohort Study (BCS70), Next Steps (1989-90), and the Millennium Cohort Study (MCS, 2000-02). This site provides technical documentation and access information for researchers.

See our data resource profile paper for background.

CLS Cohort Timeline

Data Access

Pseudonymised genomic data and polygenic indices/scores are available without charge to the global research community upon data application request.

For information about how to access CLS genetic data please see the Data Access page.

Contribute to GWAS or other consortia

We are happy to contribute to GWAS or other consortia, please contact us.

Genetic data

There are two main types of genomic data available to researchers at present: genotype array data and genotype array data imputed to sequence level density. Imputation has been performed several times as new sequenced reference panels become available.

Updates:

  • CLS polygenic indexes now available via the UKDS: For further information see the PGI page.
  • Resource profile paper now published: See here.
  • 2024: TOPMed imputation completed across all cohorts